Santa Fe is the capital city of province of Santa Fe, Argentina. It sits in northeastern Argentina, near the junction of the Paraná and Salado rivers. It lies opposite the city of Paraná, to which it is linked by the Hernandarias Subfluvial Tunnel. The city is also connected by canal with the port of Colastiné on the Paraná River. Santa Fe has about 369,000 inhabitants as per the 2001 census . The metropolitan area has a population of 454,238, making it the ninth largest in Argentina.
Santa Fe is the commercial and transportation center for a rich agricultural area that produces grain, vegetable oils, and meats. The city is the seat of the Catholic University of Santa Fe (inaugurated in 1959), the National University of the Littoral (first founded as the Provincial University in 1889, and which changed to its current name in 1919), several museums, and a number of buildings erected during colonial times.
Santa Fe is linked to Rosario (170 km to the south), the largest city in the province, by the Brigadier Estanislao López Highway and by National Route 11, which continues south towards Buenos Aires.
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